Apparatus

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890A Large Animal In Situ Test Apparatus

Model 890A in situ Large Animal Apparatus

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890A Large Animal in situ Test Apparatus

Features

  • System designed for dogs, sheep, pigs and other large animals
  • Flexible limb clamping, easily adjust location of clamp with respect to the animal's hind limb
  • Available in two configurations, isometric - force-frequency, fatigue studies and isometric/isotonic - force-frequency, fatigue, lengthening contractions (eccentric contractions), force-length, force-velocity, work, stiffness
  • 3-axis positioner provides easy positioning of the footplate with respect to the animal
  • Fine translation stage on sensor allows accurate setting of resting tension
  • T-slot design provides flexibility to easily add additional apparatus
  • Corrosion resistant materials used throughout

The 890A in situ/in vivo test system was designed to enable physiology researchers to easily test hindlimb  muscle strength and muscle response to repeated eccentric contractions with large live animals.

The 890A apparatus consists of an integrated assembly that provides pelvic limb fixation, animal footplate, force sensor and/or motor and linear translators to adjust footplate position with respect to the animal's pelvic limb. The apparatus can be used with either hind limb.

All parts are manufactured from corrosion resistant materials (anodized aluminum, stainless steel, and Delrin). The main frame is manufactured from an extrusion with T-slots that allow additional equipment to be easily mounted.

The position of the pelvic limb clamp can be adjusted through a large range by use of simple sliders that easily lock into place.  High-precision linear stages provide fine control of the footplate position with respect to the animal's pelvic limb.

Journal of Visualized Experiments Article

In Vivo Canine Muscle Function Assay

Martin K. Childers1, Robert W. Grange2, Joe N. Kornegay3
1Department of Neurology and Wake Forest Institute for Regenerative Medicine, Wake Forest University, 2Department of Human Nutrition, Foods and Exercise, Virginia Polytechnic Institute and State University, 3Departments of Pathology and Laboratory Medicine and Neurology and the Gene Therapy Center, University of North Carolina-Chapel Hill

Childers Jove Article

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